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Cbl-b-IN-30

CAT: 0013-GTR19273925-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273925-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cbl-b-IN-30 is an orally active inhibitor of Casitas B-lineage lymphoma-b (CBLB) . It specifically binds to CBLB and inhibits its E3 ubiquitin ligase activity, with an IC50 value of 9.1 nM. Cbl-b-IN-30 promotes IL-2 secretion (EC50 value of 187.5 nM) and enhances T cell activation. This compound also exhibits antitumor activity and can induce immune memory. It is useful for colon cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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