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Ferroptosis inducer-12

CAT: 0013-GTR19273358-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273358-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ferroptosisinducer-12 is a potent and selective inducer of ferroptosis. It demonstrates strong antiproliferative activity against HT1080 and OS-RC-2 cell lines, with IC50 values of 3 nM and 5 nM, respectively. This compound significantly inhibits GPX4 enzyme activity, induces intracellular ROS, and elevates Fe2+ levels within OS-RC-2 cells. Moreover, Ferroptosisinducer-12 markedly inhibits tumor growth in BALB/c nude mice bearing OS-RC-2 xenografts. It is applicable for cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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