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Ferroptosis inducer-8

CAT: 0013-GTR19264330-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264330-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ferroptosisinducer-8 is a ferroptosis (iron-dependent cell death) inducer with high selectivity against other cell death pathways. It induces ferroptosis by affecting ACSL4, GPX4, and FTH1, disrupting intracellular iron homeostasis and the GSH/GPX4 antioxidant defense system, leading to the accumulation of lipid peroxides. Ferroptosisinducer-8 also stimulates ROS production and can inhibit tumor growth, making it useful for research in triple-negative breast cancer (TNBC) .
CAS Number
3097194-74-3
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research
Smiles
C (N (C (CCl) =O) C1=CC (OC) =C (Cl) C (OC) =C1) C=2[C@@]3 ([C@@] (C (C (OC) =O) =CO[C@H]3OC) (CC2) [H]) [H]
Molecular Formula
C22H25Cl2NO7
Molecular Weight
486.34
Storage Conditions
-20°C
Notes
For research use only.

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