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Ferroptosis inducer-11

CAT: 0013-GTR19273056-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273056-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ferroptosisinducer-11 is an agent that induces ferroptosis, exhibiting significant cytotoxicity against HCT-116, NCM-60, and HT-29 cells with IC50 values of 0.43 μM, 3.14 μM, and 0.48 μM, respectively. It potently inhibits GPX4 enzyme activity with an IC50 of 1.86 μM. This compound induces ferroptosis and increases lipid ROS, malondialdehyde (MDA), and Fe2+ levels in colon cancer cells while reducing glutathione (GSH) levels. Ferroptosisinducer-11 is useful for colon cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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