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Pan-KRAS-IN-18

CAT: 0013-GTR19273354-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273354-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pan-KRAS-IN-18 (Compound 14-1) is a broad-spectrum KRAS inhibitor. It demonstrates potent antitumor activity, significantly inhibiting the proliferation of both wild-type and mutant cancer cells, such as KRASG12D, KRASG12V, and KRASG12C. Additionally, pan-KRAS-IN-18 effectively suppresses tumor growth in xenograft mouse models like GP2D and Panc0403.
CAS Number
3024881-00-0
Smiles
C (OC1=NC (=C2C (=N1) C[C@H] (OC2) C3=C (C (F) (F) F) C (C#CC) =CC (N) =C3F) N4CC=5N (CCC4) N=C (C (N (C ([2H]) ([2H]) [2H]) C ([2H]) ([2H]) [2H]) =O) C5Cl) [C@@]67N (CC (=C) C6) CCC7
Molecular Formula
C36H39ClF4N8O3
Molecular Weight
749.24
Storage Conditions
-20°C
Notes
For research use only.

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