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Pan-KRAS-IN-6

CAT: 0931-T88001-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T88001-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3033565-36-2
Target
Kras, Ras
Related Pathways
GPCR/G Protein, MAPK
Bioactivity
Pan-KRAS-IN-6 (compound 12) is a potent pan-KRAS inhibitor, with IC50 values of 9.79 nM for Kras G12D and 6.03 nM for Kras G12V.
Smiles
C(OC=1N=C(C2=C(N1)C(F)=C(C(Cl)=C2)C3=C4C(SC(N)=N4)=C(F)C=C3)N5CC(C)(O)COCC5)[C@@]67N(C[C@H](F)C6)CCC7
Molecular Formula
C29H30ClF3N6O3S
Molecular Weight
635.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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