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HsClpP activator-2

CAT: 0013-GTR19273120-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273120-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HsClpP activator-2 is an orally active HsClpP agonist with a KD of 40 nM. It exhibits significant inhibitory effects on small cell lung cancer (SCLC) cells, including H69 (IC50 = 0.17 μM) and H82 (IC50 = 0.19 μM) . This compound disrupts mitochondrial membrane potential (MMP), induces apoptosis (apoptosis), and promotes ROS production in H82 cells. Additionally, HsClpP activator-2 significantly suppresses tumor growth in non-SMC cell xenograft models and is applicable for research in small cell lung cancer (SCLC) .
Storage Conditions
-20°C
Notes
For research use only.

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