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SERCA2a activator 2

CAT: 0013-GTR19274480-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274480-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SERCA2a activator 2 (Compound 25) is a potent activator of SERCA2a (cardiac type) and also activates SERCA1a (skeletal muscle type) . Under [Ca2+]MAX conditions, it enhances SERCA2a ATPase activity and facilitates Ca2+ uptake with EC50 values of 4 μM and 0.80 μM, respectively. It consistently activates under near-physiological [Ca2+]MID conditions as well. Furthermore, SERCA2a activator 2 exhibits low cytotoxicity, making it useful for researching diseases such as heart failure.
Storage Conditions
-20°C
Notes
For research use only.

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