Products for Research Use Only
RegisterLogin

STING agonist-45

CAT: 0013-GTR19273053-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19273053-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
STINGagonist-45 is a selective STING agonist (EC50= 0.28 μM) that activates the innate immune response through the cGAS-STING pathway, increasing key markers such as p-TBK1 and IRF3. This compound exhibits potent STING activation in human peripheral blood mononuclear cells (PBMC), inducing type I interferons like IFN-β and downstream cytokines such as TNF-α and IL-6. In mouse models, STINGagonist-45 enhances anti-tumor immunity, inhibits tumor growth, and increases CD8+ T cell infiltration. It is applicable for research on STING-associated diseases.
CAS Number
2361424-97-5
Smiles
O=C (N) C1=CC=2N=C (NC (=O) C3=CC (=NN3CC) C) N (C2C (OC4COC4) =C1) CCC
Molecular Formula
C21H26N6O4
Molecular Weight
426.48
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19220906-01STING agonist-30
GTR19220631-01STING agonist-25
GTR19220628-01STING agonist-28
GTR19219360-01STING agonist-18
GTR19234606-01STING agonist-33
GTR19167112-01STING agonist-1
GTR19204723-01STING agonist-3
GTR19234607-01STING agonist-21
GTR19234508-01STING agonist-35
GTR19220630STING agonist-26

Alternative Products

CatalogName
HY-177338STING agonist-45
HY-149267-01STING agonist-30
463304STING Agonist 12b
HY-152958STING agonist-25
HY-152960STING agonist-27
HY-144328STING agonist-10
HY-143896-01STING agonist-7
HY-178966STING agonist-48
HY-176257STING agonist-44
HY-147834STING agonist-9

Popular Products