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PROTAC HPK1 Degrader-7

CAT: 0013-GTR19275315-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275315-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACHPK1 Degrader-7 (compound D02) is a potent and selective PROTACHPK1 degrader with a DC50 of 3.07 nM, showing selectivity for GLK. It induces HPK1 degradation in a CRBN and proteasome-dependent manner. Additionally, PROTACHPK1 Degrader-7 inhibits the phosphorylation of SLP-76 and stimulates the secretion of IL-2 and IFN-γ by human primary T cells, making it useful for immunological research.
Storage Conditions
-20°C
Notes
For research use only.

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