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PROTAC FTO degrader 1

CAT: 0013-GTR19275081-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275081-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACFTO degrader 1 is a PROTAC designed to target and degrade fat mass and obesity-associated protein (FTO) . It leverages the VHL E3 ligase and the ubiquitin-proteasome system for the selective degradation of FTO. This compound enhances m6A modifications on mRNAs related to ribosome biogenesis and promotes their YTHDF2-mediated degradation. Furthermore, PROTACFTO degrader 1 effectively inhibits cancer cell proliferation and induces apoptosis, making it a valuable candidate for cancer research, particularly in acute myeloid leukemia (AML) .
Storage Conditions
-20°C
Notes
For research use only.

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