MMAD-d8

• UNSPSC Description:

  MMAD-d8D is a deuterated form of MMAD, which is a microtubule disrupting agent.

• Target Antigen:

  ADC Cytotoxin; Microtubule/Tubulin

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C(N[C@H](C1=NC=CS1)CC2=CC=CC=C2)[C@H](C)[C@@H](OC)[C@H]3N(C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C([C@@](C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])([2H])NC([C@H](C(C)C)NC)=O)=O)C)=O)CCC3

• Molecular Weight:

  779.11

• References & Citations:

  [1]Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported