Mc-MMAD

• Description:

  Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a agent-linker conjugate for ADC.

• UNSPSC:

  12352203

• Target:

  Drug-Linker Conjugates for ADC; Microtubule/Tubulin

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Mc-MMAD.html

• Purity:

  98.39

• Solubility:

  DMSO : ≥ 100 mg/mL

• Smiles:

  O=C1N(CCCCCC(N(C)[C@H](C(N[C@@H](C(C)C)C(N(C)[C@]([C@@H](C)CC)([H])[C@@H](CC(N2[C@H]([C@H](OC)[C@H](C(N[C@@H](CC3=CC=CC=C3)C4=NC=CS4)=O)C)CCC2)=O)OC)=O)=O)C(C)C)=O)C(C=C1)=O

• Molecular Formula:

  C51H77N7O9S

• Molecular Weight:

  964.26

• References & Citations:

  [1]Antibody-drug conjugates Patent: WO 2013068874 A1

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Auristatin

• CAS Number:

  1401963-15-2