Mc-MMAD

• Description :

  Mc-MMAD is a protective group (maleimidocaproyl) -conjugated MMAD. MMAD is a potent tubulin inhibitor. Mc-MMAD is a agent-linker conjugate for ADC.

• CAS Number :

  [1401963-15-2]

• UNSPSC :

  12352203

• Target :

  Drug-Linker Conjugates for ADC; Microtubule/Tubulin

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Mc-MMAD.html

• Purity :

  98.39

• Solubility :

  DMSO : ≥ 100 mg/mL

• Smiles :

  O=C1N(CCCCCC(N(C)[C@H](C(N[C@@H](C(C)C)C(N(C)[C@]([C@@H](C)CC)([H])[C@@H](CC(N2[C@H]([C@H](OC)[C@H](C(N[C@@H](CC3=CC=CC=C3)C4=NC=CS4)=O)C)CCC2)=O)OC)=O)=O)C(C)C)=O)C(C=C1)=O

• Molecular Formula :

  C51H77N7O9S

• Molecular Weight :

  964.26

• References & Citations :

  [1]Antibody-drug conjugates Patent: WO 2013068874 A1

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  Auristatin