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Mtb-IN-12

CAT: 0013-GTR19263778-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263778-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mtb-IN-12 (Compound 5m) is a dual-target inhibitor that acts on the Mycobacterium tuberculosis enzymes CYP125 with a dissociation constant (KD) of 40 nM and an inhibition constant (KI) of 0.1 μM, and CYP142 with a KD of 160 nM and a KI of 0.05 μM. It effectively inhibits both drug-sensitive and multidrug-resistant strains of the tuberculosis bacterium, with low toxicity to macrophages, making it useful for studying anti-tuberculosis treatments.
Field of Research
Infectious Disease & Virology, Metabolism Research
Storage Conditions
-20°C
Notes
For research use only.

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