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PDE4-IN-29

CAT: 0013-GTR19263554-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263554-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDE4-IN-29 (Compound 55) is an orally active and selective inhibitor of PDE4, targeting subtypes such as PDE4A1, PDE4B2, and PDE4D3, with an IC50 value for PDE4D3 of less than 5 nM. It inhibits the degradation of cyclic adenosine monophosphate (cAMP), elevating intracellular cAMP levels and suppressing the release of inflammatory mediators like TNF-α. PDE4-IN-29 holds potential for research in inflammatory diseases such as psoriasis, atopic dermatitis, and chronic obstructive pulmonary disease.
CAS Number
2815361-45-4
Field of Research
Metabolism Research, Signal Transduction
Smiles
O=C1C=2C (C (=O) N1[C@H] (CS (C) (=O) =O) C3=CC (OCC) =C (OC) C=C3) =C (NC (C) =O) C=CC2C (CCCC) O
Molecular Formula
C27H34N2O8S
Molecular Weight
546.63
Storage Conditions
-20°C
Notes
For research use only.

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