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DM-4103

CAT: 0013-GTR19263106-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263106-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DM-4103 is a primary metabolite of Tolvaptan, predominantly metabolized by the CYP3A4 enzyme in the liver. In SCHH cells, DM-4103 inhibits the human liver transport proteins NTCP, BSEP, MRP2, MRP3, and MRP4 with IC50 values of 16.3, 4.15, 51.0, 44.6, and 4.26 μM, respectively, and affects bile acid transport. DM-4103 is applicable for research in autosomal dominant polycystic kidney disease (ADPKD) .
CAS Number
1346599-56-1
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C (O) CCC (=O) C1=CC (Cl) =CC=C1NC (=O) C2=CC=C (C=C2C) NC (=O) C=3C=CC=CC3C
Molecular Formula
C26H23ClN2O5
Molecular Weight
478.92
Storage Conditions
-20°C
Notes
For research use only.

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