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PD 158771

CAT: 0804-HY-167648Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-167648Size:1 Each
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Description
PD 158771 is an antipsychotic agent that functions as a partial agonist for D2 /D3 receptors (Ki = 42.0/13.7 nM) and as an agonist for 5-HT1A receptors (Ki = 2.6 nM) . PD 158771 can be utilized in antipsychotic research[1].
CAS Number
189152-50-9
UNSPSC
12352005
Target
5-HT Receptor; Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pd-158771.html
Smiles
C1(N[C@H]2CC[C@H](CCN3CCN(C4=CC=CC=C4)CC3)CC2)=NC=CC=N1
Molecular Formula
C22H31N5
Molecular Weight
365.52
References & Citations
[1]Akunne HC, et al. PD 158771, a potential antipsychotic agent with D (2) /D (3) partial agonist and 5-HT (1A) agonist actions. I. Neurochemical effects. Neuropharmacology. 2000 Apr 27;39 (7) :1197-210.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; D2 Receptor; D3 Receptor; mLAG-3

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