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PROTAC BRD4 Degrader-32

CAT: 0013-GTR19257716-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257716-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACBRD4 Degrader-32 (Compound 22) is a potent BRD4 PROTAC degrader with a DC50 of 0.20 nM. It employs a unique carbon-carbon linker to connect the BRD4 binding domain with the CRBN binding domain, forming a ternary complex that induces BRD4 ubiquitination and facilitates proteasomal degradation. PROTACBRD4 Degrader-32 holds promise for research into BRD4-related cancers, such as hematological malignancies.
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C42H42ClN5O5
Storage Conditions
-20°C
Notes
For research use only.

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