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Cath-L-dBET1

CAT: 0013-GTR19258656-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258656-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cath-L-dBET1 is a PROTAC degrader targeting BRD4. It has an IC50 value of 2.8 μM in MDA-MB-231 cells. Activated by cathepsin L (Cath-L), Cath-L-dBET1 recruits E3 ubiquitin ligase to degrade BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable for antitumor research.
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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