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DBET1

CAT: 0013-GTR19170171-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170171-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DBET1 is a cereblon-directed PROTAC that degrades BET proteins with an in vitro EC50 of 430 nM, leading to apoptosis. This molecular tool is widely used in oncology research to study BET protein function and has demonstrated activity in cellular and animal models of cancer.
CAS Number
1799711-21-9
Product Name Alternative
PROTACs, dBET1, dBET-1, dBET 1, BET, inhibit, Epigenetic Reader Domain, EpigeneticReaderDomain, Inhibitor
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
98.02% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (4.2 mM) ; DMSO:50 mg/mL (63.67 mM) ; H2O:Insoluble; Ethanol:5 mg/mL (6.37 mM)
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCCCNC (COC4=C5C (C (=O) N (C5=O) C6C (=O) NC (=O) CC6) =CC=C4) =O) =O) N=C2C7=CC=C (Cl) C=C7) =NN=C3C) SC1C
Molecular Formula
C38H37ClN8O7S
Molecular Weight
785.27
Storage Conditions
-20°C
Notes
For research use only.

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