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EGFR-IN-160

CAT: 0013-GTR19257632-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257632-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-160 is an EGFR inhibitor with IC50 values of 1.62, 0.49, and 0.98 μM for EGFRWT, EGFRT790M, and EGFRL858R/T790M/C797S, respectively. It can induce cell cycle arrest at the G2/M and S phases and apoptosis (Apoptosis) in NCI-H522 cells, demonstrating anticancer properties. Additionally, EGFR-IN-160 exhibits antioxidant activity against DPPH (IC50: 12.11 μM) and H2O2 (IC50: 8.89 μM) .
CAS Number
2172879-84-2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O=C1N=C (C=C (N1) C=2C=CC (O) =C (OC) C2) C=3OC=CC3
Molecular Formula
C15H12N2O4
Molecular Weight
284.27
Storage Conditions
-20°C
Notes
For research use only.

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