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COX-2-IN-51

CAT: 0013-GTR19249803-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249803-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
COX-2-IN-51 is a potent and selective COX-2 inhibitor (IC50 = 70.7 nM) that suppresses inflammatory mediators like PGE2 and NO by blocking the NF-κB pathway. It demonstrates significant anti-inflammatory and analgesic efficacy in murine models with an improved gastrointestinal safety profile relative to indomethacin.
CAS Number
3064260-49-4
Field of Research
Immunology & Inflammation, Neuroscience, Signal Transduction
Smiles
FC1=CC=C2OC (OCCC3=CSC=C3) (C (=CC2=C1) C=4C=CC (OC) =CC4) C (F) (F) F
Molecular Formula
C23H18F4O3S
Molecular Weight
450.446
Storage Conditions
-20°C
Notes
For research use only.

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