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DOTAP methylsulfate

CAT: 0013-GTR19248592-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19248592-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DOTAP methylsulfate is a cationic lipid reagent and a trimethylammonium cation derivative, with two octadecanoic fatty acid chains in its molecular structure, each containing one unsaturated alkene bond. DOTAP can self-assemble with negatively charged nucleic acids such as DNA via electrostatic interactions to form complexes, which enter cells through electrostatic adsorption and endocytosis. The hydrophobic domain of DOTAP promotes endosomal membrane fusion and facilitates nucleic acid release into the cytoplasm, thereby achieving efficient gene delivery. Currently, DOTAP methylsulfate is widely used in gene therapy, in vitro cell transfection, non-viral vector construction, and related research fields.
CAS Number
144189-73-1
Field of Research
Metabolism Research
Purity
97.00% (May vary between batches)
Smiles
S (OC) (=O) (=O) [O-].C (OC (CCCCCCC/C=C\CCCCCCCC) =O) (COC (CCCCCCC/C=C\CCCCCCCC) =O) C[N+] (C) (C) C
Molecular Formula
C43H83NO8S
Molecular Weight
774.19
Storage Conditions
-20°C
Notes
For research use only.

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