MsbA-IN-2

CAT: 0804-HY-144280Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144280Size:1 Each
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Description
MsbA-IN-2 (compound 12) is a potent lipopolysaccharide transporter MsbA inhibitor with an IC50 of 2 nM for E. coli MsbA[1].
CAS Number
[2909443-16-7]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/msba-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(O)/C=C/C1=C(C2CC2)C3=CC(O[C@H](C4=C(Cl)C=CC=C4Cl)C)=CC=C3N=C1
Molecular Formula
C23H19Cl2NO3
Molecular Weight
428.31
References & Citations
[1]Verma VA, et al. Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity. J Med Chem. 2022;65 (5) :4085-4120.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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