Products for Research Use Only

CKR-49-17

CAT: 0804-HY-162043-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-162043-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CKR-49-17 is an activator of CK1γ2. CKR-49-17 decreases C99 and β-amyloid levels. CKR-49-17 can be used in the research of Alzheimer's disease (AD) [1].
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ckr-49-17.html
Purity
98.40
Solubility
DMSO : 4.35 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C(CNC2CCNCC2)C=C1)NC3=NC4=CC=C(C#N)C=C4S3
Molecular Formula
C21H21N5OS
Molecular Weight
391.49
References & Citations
[1]Victor Hugo Bustos, et al. Rational Development of a Small-Molecule Activator of CK1γ2 That Decreases C99 and Beta-Amyloid Levels. ACS Chem Biol. 2023.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported