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ES-072

CAT: 0013-GTR19239275-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239275-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ES-072 is an orally active, selective EGFR-T790M inhibitor that induces PD-L1 degradation via GSK3α-mediated phosphorylation and ARIH1-dependent ubiquitination. This dual action suppresses NSCLC cell proliferation in vitro and enhances anti-tumor immunity, supporting its research in targeted therapy and immuno-oncology.
CAS Number
2089721-94-6
Field of Research
Cardiovascular Research, Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (C=C) NC1=CC=CC (=C1) NC2=NC (=NC=C2C (F) (F) F) NC=3C=CC (=NC3OC) N4CCN (C) CC4
Molecular Formula
C25H27F3N8O2
Molecular Weight
528.53
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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T200087-01ES-072
HY-101634-01ABT-072
HY-178738GC-072
T205305-01HYS-072
T32331-01JWH 072
TRC-J211380-100MGJWH-072
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A20177-100ABT-072 100mg
A20177-50ABT-072 50mg
HY-101634RABT-072 (Standard)

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