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PROTAC KSP-IN-1

CAT: 0013-GTR19241461-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241461-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACKSP-IN-1 (Compound 21) is a potent KSP-targeting PROTAC degrader with a DC50 of 114.8 nM in HCT-116 cells. It demonstrates strong anti-proliferative activity (IC50 = 10 nM), induces G2/M arrest and apoptosis in vitro, and shows in vivo antitumor efficacy in mouse models, supporting its use in cancer research.
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C48H51N5O8S
Molecular Weight
858.01
Storage Conditions
-20°C
Notes
For research use only.

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