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PROTAC PTPN2 degrader-2

CAT: 0013-GTR19230666-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230666-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC PTPN2 degrader-2 (example 187B) is a potent and selective small molecule degrader of PTPN2, a phosphatase implicated in oncology and immunometabolism. Its utility has been demonstrated in cellular assays for cancer immunotherapy research and shows potential for in vivo metabolic disease studies.
CAS Number
2912307-38-9
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C1C2=C3C (N1[C@@H]4C (=O) NC (=O) CC4) =CC=C (C3=CC=C2) C5CCN (C (NC6=CC (CS (=O) (=O) N7C (C) (C) C[C@@H] (NC8=CC (=CC=C8) C9=C (Cl) C (OCC (O) =O) =C (C (O) =O) S9) CC7) =CC=C6) =O) CC5
Molecular Formula
C49H49ClN6O11S2
Molecular Weight
997.53
Storage Conditions
-20°C
Notes
For research use only.

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