Products for Research Use Only

Cbl-b-IN-8

CAT: 0013-GTR19230162-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230162-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cbl-b-IN-8 (Compound 293) is a potent dual inhibitor of the E3 ubiquitin ligases Cbl-b and c-Cbl, with IC50 values of 5.5 nM and 7.8 nM, respectively. This small molecule is a valuable research tool for investigating immune regulation and oncogenic signaling pathways in both cellular and animal models.
CAS Number
2815223-33-5
Field of Research
Cancer Biology, Protein Biochemistry
Smiles
C (C1 (COC1) C=2C=C (N=C (OC3CCCC3) C2) N4CC=5C (C4=O) =CC (CN6[C@@H] ([C@H] (C) C) CN (C) CC6) =CC5C (F) (F) F) C=7N (C) C=NN7
Molecular Formula
C35H44F3N7O3
Molecular Weight
667.76
Storage Conditions
-20°C
Notes
For research use only.