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Cbl-b-IN-10

CAT: 0013-GTR19230160-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230160-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cbl-b-IN-10 (Compound 463) is a potent dual inhibitor of Cbl-b and c-Cbl with IC50 values of 6.0 nM and 3.5 nM, respectively. This small molecule is a valuable research tool for studying E3 ubiquitin ligase function in immune cell signaling and has been utilized in both cellular and animal models of autoimmunity and cancer.
CAS Number
2815225-12-6
Field of Research
Cancer Biology, Protein Biochemistry
Smiles
C (C1 (CCC1) C2=CC (=CC (NCC) =C2) N3CC=4C (C3=O) =CC (CNC5 (C) CCC5) =CC4C (F) (F) F) C=6N (C) C=NN6
Molecular Formula
C31H37F3N6O
Molecular Weight
566.66
Storage Conditions
-20°C
Notes
For research use only.

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