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BMI-135

CAT: 0804-HY-164463Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-164463Size:1 Each
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Description
BMI-135 is a selective estrogen mimic, that exhibits agonist activity for estrogen receptor. BMI-135 induces rapid endoplasmic reticulum stress response (UPR) and apoptosis in breast cancer cells[1].
CAS Number
1608099-90-6
UNSPSC
12352100
Target
Apoptosis; Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Apoptosis; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bmi-135.html
Smiles
O=C(C1=CC=C(C#C)C=C1)C2=C(C3=CC=C(F)C=C3)C4=C(S2)C=C(O)C=C4
Molecular Formula
C23H13FO2S
Molecular Weight
372.41
References & Citations
[1]Abderrahman B, et al., Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Mol Cancer Ther. 2021 Jan;20 (1) :11-25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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