BMI-1026

• Description:

  BMI-1026 is a cyclin-dependent kinase 1 (Cdk1) inhibitor with IC50 of 2.3 nM. BMI-1026 induces apoptosis by arresting the G2-M phase[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; CDK

• Type:

  Reference compound

• Related Pathways:

  Apoptosis; Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/bmi-1026.html

• Smiles:

  OC1=CC=C (C=C1C2=NC (N) =NC=C2) C3=NC (N) =NC=C3

• Molecular Formula:

  C14H12N6O

• Molecular Weight:

  280.28

• References & Citations:

  [1]Seong YS, et al. Characterization of a novel cyclin-dependent kinase 1 inhibitor, BMI-1026. Cancer Res. 2003 Nov 1;63 (21) :7384-91. Erratum in: Cancer Res. 2004 May 15;64 (10) :3725.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CDK1

• CAS Number:

  477726-77-5