Products for Research Use Only

TM2 TEAD inhibitor

CAT: 0013-GTR19219794-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219794-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TM2 is a potent, reversible TEAD inhibitor that blocks auto-palmitoylation (IC50: 38 nM TEAD4) and disrupts TEAD-YAP transcriptional activity. It demonstrates significant antiproliferative effects in YAP-dependent cancer cells and potently inhibits the growth of YAP-driven liver organoids in vitro, supporting its investigation as an anticancer therapeutic.
CAS Number
1008768-41-9
Product Name Alternative
TEAD-IN-8
Field of Research
Musculoskeletal & Connective Tissue Research; Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
99.91% (May vary between batches)
Smiles
O=C (NC=1C=CC=CC1) N2CCN (C (=O) C=3C=CC=C (OCCC4CCCCC4) C3) CC2
Molecular Formula
C26H33N3O3
Molecular Weight
435.57
Storage Conditions
-20°C
Notes
For research use only.