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JMJD3/HDAC-IN-1

CAT: 0013-GTR19218966-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218966-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JMJD3/HDAC-IN-1 (A5b) is a dual inhibitor of JMJD3 and HDAC1 (IC50 = 16 nM) . It modulates histone marks by inducing H3K27 hypermethylation and H3K9 hyperacetylation, promoting apoptosis via caspase-7/PARP cleavage. This compound is used in cancer research to study epigenetic mechanisms and has shown efficacy in inhibiting cell proliferation, migration, and invasion in vitro.
CAS Number
2883046-06-6
Field of Research
Cell Biology, Epigenetics & Chromatin, Metabolism Research; Epigenetics & Chromatin, Molecular Biology
Smiles
N (CCCCCC (NO) =O) C=1N=C (N=C (C1) N2CCCCCC2) C3=CC=CC=N3
Molecular Formula
C21H30N6O2
Molecular Weight
398.5
Storage Conditions
-20°C
Notes
For research use only.

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