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SB02024

CAT: 0013-GTR19210121-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19210121-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB02024 is a VPS34 inhibitor that blocks autophagy, activates cGAS-STING signaling, and sensitizes tumors to STING agonists. It demonstrates efficacy in reducing breast cancer xenograft growth and, in vitro, significantly enhances the cytotoxicity of Sunitinib and Erlotinib in monolayer and spheroid models of MDA-MB-231 and MCF-7 cells.
CAS Number
2126737-28-6
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
[C@] (F) (F) (F) [C@@H]1N (CCCC1) C2=CC (=CC (=O) N2) N3[C@H] (C) COCC3
Molecular Formula
C16H22F3N3O2
Molecular Weight
345.36
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T69888-01SB02024
HY-122891A-01(2S) -SB02024

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