(2S) -SB02024

• Description:

  (2S) -SB02024 (SB02877), the S-enantiomer of SB02024 (HY-122891), is a Vps34 inhibitor[1].

• UNSPSC:

  12352005

• Target:

  PI3K

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Smiles:

  O=C1C=C(N2[C@H](C)COCC2)C=C(N3[C@H](C(F)(F)F)CCCC3)N1

• Molecular Formula:

  C16H22F3N3O2

• Molecular Weight:

  345.36

• References & Citations:

  [1]Noman MZ, et al. Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy. Sci Adv. 2020 Apr 29;6 (18) :eaax7881.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2126737-29-7]