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APTO-253 isomer

CAT: 0013-GTR19209150-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19209150-01Size:25 mg
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Description
APTO-253 isomer is a 6-fluoro-substituted analog of the MTF-1 inhibitor APTO-253 (LOR-253) . It functions by inhibiting MTF-1 to induce KLF4 expression, leading to cell cycle arrest via cyclin D1 downregulation. This compound is used in cancer research, with studies demonstrating its activity in both cellular and animal models of leukemia and solid tumors.
CAS Number
1422826-80-9
Smiles
CC1=C (C=2NC=3C (=C4C (=C5C3C=CC=N5) N=CC=C4) N2) C=6C (N1) =CC (F) =CC6
Molecular Formula
C22H14FN5
Molecular Weight
367.38
Storage Conditions
-20°C
Notes
For research use only.

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