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AC 253

CAT: 0013-GTR19029156Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19029156Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This small molecule AMY3 receptor antagonist inhibits adrenomedulin-stimulated cAMP production in vitro. It protects neuronal cultures from oligomeric Aβ-induced calcium dysregulation, aberrant PKA/MAPK/Akt signaling, and cell death, while also blocking Aβ's electrophysiological effects. Its research applications include studying amyloid toxicity mechanisms and potential neuroprotective strategies in Alzheimer's disease models.
Field of Research
Neuroscience
Molecular Weight
2847.11
Storage Conditions
-20°C
Notes
For research use only.

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