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Bio-THZ1

CAT: 0013-GTR19206428-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206428-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bio-THZ1 is a biotin-conjugated derivative of THZ1, a potent, selective, and irreversible covalent inhibitor of CDK7 (IC50 = 3.2 nM) . This tool compound is widely used in proteomics and target engagement studies, facilitating research into transcription and cell cycle regulation in both cellular and animal models.
CAS Number
1604811-14-4
Field of Research
Cell Biology
Smiles
[H][C@]12CS[C@@H] (CCCCC (=O) NCCOCCOCCOCCNC (=O) NCCCN (C) C\C=C\C (=O) Nc3ccc (cc3) C (=O) Nc3cccc (Nc4ncc (Cl) c (n4) -c4c[nH]c5ccccc45) c3) [C@@]1 ([H]) NC (=O) N2
Molecular Formula
C52H65ClN12O8S
Molecular Weight
1053.67
Storage Conditions
-20°C
Notes
For research use only.

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