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THZ1

CAT: 0013-GTR19171028-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171028-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
THZ1 is a potent and selective covalent CDK7 inhibitor with an IC50 of 3.2 nM. Its mechanism involves targeting a specific cysteine residue, ensuring high selectivity. This compound is widely used in vitro and in vivo for cancer research, particularly in studies of transcriptional regulation and cell cycle progression.
CAS Number
1604810-83-4
Product Name Alternative
THZ 1, THZ1, THZ-1, THZ1 2HCl, CDK7 inhibitor, CDK7, CDK
Field of Research
Cell Biology
Purity
>97%
Bioactivity
CDK7 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
CN (C) C\C=C\C (=O) Nc1ccc (cc1) C (=O) Nc1cccc (Nc2ncc (Cl) c (n2) -c2c[nH]c3ccccc23) c1
Molecular Formula
C31H28ClN7O2
Molecular Weight
566.05
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(E) -N- (3- ((5-chloro-4- (1H-indol-3-yl) pyrimidin-2-yl) amino) phenyl) -4- (4- (dimethylamino) but-2-enamido) benzamide

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