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THZ1 Hydrochloride

CAT: 0013-GTR19212739-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212739-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
THZ1 hydrochloride is a potent and selective covalent inhibitor of CDK7 (IC50 = 3.2 nM), with additional activity against CDK12/13, resulting in suppression of MYC expression. It is a valuable chemical probe for studying transcription, cell cycle progression, and oncology research in both cellular and animal models.
Field of Research
Cell Biology
Smiles
CN (C) C/C=C/C (=O) NC1=CC=C (C=C1) C (=O) NC2=CC=CC (=C2) NC3=NC=C (C (=N3) C4=CNC5=CC=CC=C54) Cl.Cl
Molecular Formula
C31H29Cl2N7O2
Molecular Weight
602.51
Storage Conditions
-20°C
Notes
For research use only.

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