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PKF050-638

CAT: 0804-HY-114597-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114597-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
528893-52-9
Product Name Alternative
CXD101
UNSPSC Description
PKF050-638 is a potent and selective inhibitor of HIV-1 Rev (IC50=0.04 μM). PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction[1].
Target Antigen
CRM1; HIV
Type
Reference compound
Related Pathways
Anti-infection;Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pkf050-638.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC)/C=C\N1N=CN=C1C2=CC(Cl)=CC=C2N
Molecular Weight
292.72
References & Citations
[1]Daelemans D, et al. A synthetic HIV-1 Rev inhibitor interfering with the CRM1-mediated nuclear export. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14440-5. Epub 2002 Oct 9.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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