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BRD4 degrader AT1

CAT: 0013-GTR19188350Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188350Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AT1 is a potent and selective PROTAC degrader of BRD4, exhibiting a cellular Kd of 44 nM for the BD2 domain. This tool compound is widely used in vitro and in vivo to investigate BRD4 biology, epigenetic signaling, and oncology research.
CAS Number
2098836-45-2
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
CC1=C (SC2=C1C (=N[C@H] (C3=NN=C (N32) C) CC (=O) NCCCCCCSC (C) (C) [C@@H] (C (=O) N4C[C@@H] (C[C@H]4C (=O) NCC5=CC=C (C=C5) C6=C (N=CS6) C) O) NC (=O) C) C7=CC=C (C=C7) Cl) C
Molecular Formula
C48H58ClN9O5S3
Molecular Weight
972.68
Storage Conditions
-20°C
Notes
For research use only.

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