Products for Research Use Only

TK-129

CAT: 0013-GTR19187753-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19187753-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TK-129 is a potent, orally bioavailable KDM5B inhibitor (IC50 = 44 nM) with a low-toxicity profile. It exhibits cardioprotective effects by disrupting the KDM5B-associated Wnt pathway, reducing myocardial fibrosis and remodeling in isoprenaline-induced in vivo models, and attenuating Ang II-induced cardiac fibroblast activation in vitro for cardiovascular disease research.
Field of Research
Epigenetics & Chromatin
Molecular Formula
C15H23N5O2
Molecular Weight
305.38
Storage Conditions
-20°C
Notes
For research use only.