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Dasatinib metabolite M6

CAT: 0804-HY-131669-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-131669-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib. Dasatinib is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase inhibitor[1].
CAS Number
910297-53-9
Product Name Alternative
Dasatinib carboxylic acid
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/dasatinib-metabolite-m6.html
Purity
99.64
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)CN1CCN(C2=NC(C)=NC(NC3=NC=C(C(NC4=C(C)C=CC=C4Cl)=O)S3)=C2)CC1
Molecular Formula
C22H24ClN7O3S
Molecular Weight
501.99
References & Citations
[1]Lisa J Christopher, et al. Biotransformation of [14C]dasatinib: in vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys. Drug Metab Dispos. 2008 Jul;36 (7) :1341-56.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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