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FTI-277 hydrochloride

CAT: 0013-GTR19174726-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174726-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FTI-277 hydrochloride is a potent and selective farnesyltransferase (FTase) inhibitor with an IC50 of 500 pM, exhibiting approximately 100-fold selectivity over GGTase I. It is widely used in cancer research to study Ras signaling pathways and has been applied in both in vitro and in vivo models to investigate tumor growth inhibition.
CAS Number
180977-34-8
Product Name Alternative
Inhibit, Inhibitor, Farnesyl Transferase, GGTase I, FTI 277, FTI 277 HCl, FTI 277 Hydrochloride, FTI 277 hydrochloride, FTI277, FTI-277, FTI277 Hydrochloride, FTI277 hydrochloride, FTI-277 Hydrochloride, Ftase, Apoptosis, Ras
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.57% (May vary between batches)
Solubility
DMSO:145 mg/mL (299.54 mM) ; H2O:14 mg/mL (28.92 mM) ; Ethanol:12 mg/mL (24.79 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.82 mM)
Smiles
Cl.Cl.COC (=O) C (CCSC) NC (=O) c1ccc (NCC (N) CS) cc1-c1ccccc1
Molecular Formula
C22H30ClN3O3S2
Molecular Weight
484.07
Storage Conditions
-20°C
Notes
For research use only.

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