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FTI 277 TFA

CAT: 0013-GTR19188513Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19188513Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FTI 277 TFA is a potent farnesyltransferase (FTase) inhibitor (IC50 = 0.5 nM) that blocks Ras protein processing and MAPK signaling. It exhibits broad antiproliferative activity against various tumor cell lines, including human malignant gliomas, making it a valuable tool for investigating Ras-driven oncogenesis in both cellular and animal models.
CAS Number
1217447-06-7
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
OC (=O) C (F) (F) F.COC (=O) [C@H] (CCSC) NC (=O) c1ccc (NC[C@@H] (N) CS) cc1-c1ccccc1
Molecular Formula
C24H30F3N3O5S2
Molecular Weight
561.64
Storage Conditions
-20°C
Notes
For research use only.

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