PF-06465603

• Description:

  PF-06465603 is a highly potent and selective ATP-competitive kinase inhibitor and a class 1 PI3K and mTOR inhibitor. PF-06465603 is a metabolite of PF-04691502 with a terminal carboxylic acid structure[1].

• UNSPSC:

  12352005

• Target:

  MTOR; PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pf-06465603.html

• Smiles:

  O=C(O)CO[C@@H]1CC[C@@H](N(C2=NC(N)=NC(C)=C2C=C3C4=CC=C(OC)N=C4)C3=O)CC1

• Molecular Formula:

  C22H25N5O5

• Molecular Weight:

  439.46

• References & Citations:

  [1]Structure-based design, SAR analysis and antitumor activity of PI3K/ mTOR dual inhibitors from 4-methylpyridopyrimidinone series

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1431626-44-6]