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PF-06465603

CAT: 0804-HY-117923Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117923Size:1 Each
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Description
PF-06465603 is a highly potent and selective ATP-competitive kinase inhibitor and a class 1 PI3K and mTOR inhibitor. PF-06465603 is a metabolite of PF-04691502 with a terminal carboxylic acid structure[1].
CAS Number
1431626-44-6
UNSPSC
12352005
Target
MTOR; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pf-06465603.html
Smiles
O=C(O)CO[C@@H]1CC[C@@H](N(C2=NC(N)=NC(C)=C2C=C3C4=CC=C(OC)N=C4)C3=O)CC1
Molecular Formula
C22H25N5O5
Molecular Weight
439.46
References & Citations
[1]Structure-based design, SAR analysis and antitumor activity of PI3K/ mTOR dual inhibitors from 4-methylpyridopyrimidinone series
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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MBS5778062PF-06465603
MBS579460PF-03084014 (PF-3084014)
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A8499-50PF-04691502
B8018-100PF 1022A
BA4631-10PF-739
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