Products for Research Use Only
RegisterLogin

Ac-DMLD-CMK

CAT: 0013-GTR19133759-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19133759-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ac-DMLD-CMK is a peptide designed to target the caspase3-Gsdme signaling pathway in mice. It specifically inhibits the activation of caspase 3 and Gsdme, preventing the cleavage of Gsdme by caspase 3, which reduces pyroptosis. This process helps alleviate damage to renal tubular epithelial cells and decrease the secretion of inflammatory cytokines. Ac-DMLD-CMK can lower serum creatinine and blood urea nitrogen levels in mice induced by Cisplatin, thereby mitigating the progression of renal dysfunction. It holds potential for research into chemotherapy-induced nephrotoxicity.
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry
Molecular Weight
567.053
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19036310-01Ac-FEID-CMK
GTR19191112-01Ac-FLTD-CMK
GTR19066452-01Ac-VAD-CMK
GTR19066443-01Ac-YVAD-CMK
GTR19063107-01Ac-VAD-CMK
GTR19150340-01Ac-KVPL-CMK
GTR19244076-01Ac-FLTD-CMK
GTR19030114-01Ac-YVAD-CMK
GTR19036309-01Ac-FEID-CMK TFA
GTR19036607-01Ac-DEVD-CMK TFA

Alternative Products

CatalogName
TP3236-01Ac-DMLD-CMK
HY-P10939A-01Ac-DMLD-CMK (TFA)
HY-P0034-01Ac-DEVD-CMK
HY-16990-01Ac-YVAD-cmk
MBS5818165Ac-FEID-CMK
S9817-10mM/1mLAc-FLTD-CMK
TP2535-01Ac-VAD-CMK
HY-204478Ac-KVPL-CMK

Popular Products