FNC-TP

CAT: 0804-HY-139262-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-139262-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

FNC-TP is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV[1]. FNC-TP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

CAS Number

2457357-99-0

UNSPSC

12352005

Target

HBV; HCV; HIV; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fnc-tp.html

Purity

99.92

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

O=P(O)(O)OP(OP(OC[C@]1(O[C@](N2C(N=C(C=C2)N)=O)([H])[C@H]([C@@H]1O)F)N=[N+]=[N-])(O)=O)(O)=O

Molecular Formula

C9H14FN6O13P3

Molecular Weight

526.16

References & Citations

[1]Sun L, et, al. Mechanistic Insight into Antiretroviral Potency of 2'-Deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a Long-Lasting Effect on HIV-1 Prevention. J Med Chem. 2020 Aug 13;63 (15) :8554-8566.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HIV-1

Related Products

Catalog	Name
HY-101857-01	TP-020
HY-100517-01	TP-472
HY-119127	TP-680
HY-114224	TP-271
HY-143518-01	TP-16
HY-138561	EFdA-TP
HY-N10168	TP-1161
HY-118522	TP-110
HY-101126-01	TP-3654
HY-131979-01	TP-040

Alternative Products

Catalog	Name
T40120	FNC-TP
MBS5806850	FNC-TP trisodium
AES-0407-100	FNC Coating Mix®
407	FNC Coating Mix®, 50 ml
0407	FNC Coating Mix®, 100 ml
AES-0407H-100	FNC Coating Mix® – Human Proteins
0407H	FNC Coating Mix® - Human Proteins, 100ml
BA4814-5	TP-064
BA3828-1	TP-1287
BA7972-5	TP-004

FNC-TP

Related Products

Alternative Products

Popular Products